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MRGPRE Protein

MRGPRE Origin: Human Host: Mammalian Cells Synthetic Nanodisc
Catalog No. ABIN7538372
  • Target See all MRGPRE Proteins
    MRGPRE (MAS-Related GPR, Member E (MRGPRE))
    Protein Type
    Synthetic Nanodisc
    Origin
    • 2
    • 1
    Human
    Source
    • 2
    • 1
    Mammalian Cells
    Purpose
    Human MRGRE full length protein-synthetic nanodisc
    Characteristics
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • Comment

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    MRGPRE (MAS-Related GPR, Member E (MRGPRE))
    Alternative Name
    MRGRE (MRGPRE Products)
    Synonyms
    GPR167 Protein, MRGE Protein, C130069N09Rik Protein, Ebrt3 Protein, MrgE Protein, MAS related GPR family member E Protein, MAS-related GPR, member E Protein, MRGPRE Protein, Mrgpre Protein
    Background
    Orphan receptor. May regulate nociceptor function and/or development, including the sensation or modulation of pain.[UniProtKB/Swiss-Prot Function]
    Molecular Weight
    The human full length MRGRE protein has a MW of 34.3kDa
    UniProt
    Q86SM8
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