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GHRHR Protein

GHRHR Origin: Human Host: Mammalian Cells Synthetic Nanodisc
Catalog No. ABIN7538314
  • Target See all GHRHR Proteins
    GHRHR (Growth Hormone Releasing Hormone Receptor (GHRHR))
    Protein Type
    Synthetic Nanodisc
    Origin
    • 2
    • 1
    Human
    Source
    • 2
    • 1
    Mammalian Cells
    Purpose
    Human GHRHR full length protein-synthetic nanodisc
    Characteristics
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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    Discover our top product GHRHR Protein
  • Comment

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    GHRHR (Growth Hormone Releasing Hormone Receptor (GHRHR))
    Alternative Name
    GHRHR (GHRHR Products)
    Synonyms
    GHRFR Protein, GRFR Protein, IGHD1B Protein, Ghrfr Protein, lit Protein, little Protein, GHRHREC Protein, GHRH-R Protein, growth hormone releasing hormone receptor Protein, GHRHR Protein, Ghrhr Protein
    Background
    This gene encodes a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in this gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature. [provided by RefSeq, Jun 2010]
    Molecular Weight
    The human full length GHRHR protein has a MW of 47.4kDa
    UniProt
    Q02643
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Hormone Transport, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process
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