GPRC5A Protein
-
- Target See all GPRC5A Proteins
- GPRC5A (G Protein-Coupled Receptor, Family C, Group 5, Member A (GPRC5A))
- Protein Type
- Synthetic Nanodisc
-
Origin
- Human
-
Source
- Mammalian Cells
- Purpose
- Human RAI3 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product GPRC5A Protein
-
-
- Comment
-
Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
-
- Target
- GPRC5A (G Protein-Coupled Receptor, Family C, Group 5, Member A (GPRC5A))
- Alternative Name
- RAI3 (GPRC5A Products)
- Synonyms
- GPCR5A Protein, RAI3 Protein, RAIG1 Protein, Rai3 Protein, Raig1 Protein, G protein-coupled receptor class C group 5 member A Protein, G protein-coupled receptor, family C, group 5, member A Protein, G protein-coupled receptor, class C, group 5, member A Protein, GPRC5A Protein, Gprc5a Protein
- Background
- This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation. [provided by RefSeq, Jul 2008]
- Molecular Weight
- The human full length RAI3 protein has a MW of 40.3kDa
- UniProt
- Q8NFJ5
-