GPR78 Protein
GPR78
Origin: Human
Host: Mammalian Cells
Synthetic Nanodisc
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- Target See all GPR78 Proteins
- GPR78 (G Protein-Coupled Receptor 78 (GPR78))
- Protein Type
- Synthetic Nanodisc
- Origin
- Human
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Source
- Mammalian Cells
- Purpose
- Human GPR78 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product GPR78 Protein
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G Protein-Coupled Receptor 78 (GPR78) (AA 1-363) protein (GST tag)
GPR78 Origin: Human Host: Wheat germ Recombinant WB, AP, ELISA, AA
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- GPR78 (G Protein-Coupled Receptor 78 (GPR78))
- Alternative Name
- GPR78 (GPR78 Products)
- Synonyms
- GPR78 Protein, G protein-coupled receptor 78 Protein, GPR78 Protein
- Background
- The protein encoded by this gene belongs to the G protein-coupled receptor family, which contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. This is an orphan receptor, which displays significant level of constitutive activity. Association analysis shows preliminary evidence for the involvement of this gene in susceptibility to bipolar affective disorder and schizophrenia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011]
- Molecular Weight
- The human full length GPR78 protein has a MW of 39.3kDa
- UniProt
- Q96P69
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