GPR62 Protein
GPR62
Origin: Human
Host: Mammalian Cells
Synthetic Nanodisc
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- Target See all GPR62 Proteins
- GPR62 (G Protein-Coupled Receptor 62 (GPR62))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- Mammalian Cells
- Purpose
- Human GPR62 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product GPR62 Protein
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G Protein-Coupled Receptor 62 (GPR62) (AA 314-368) protein (GST tag)
GPR62 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- GPR62 (G Protein-Coupled Receptor 62 (GPR62))
- Alternative Name
- GPR62 (GPR62 Products)
- Synonyms
- GPR62 Protein, GPCR8 Protein, KPG_005 Protein, 4933402E03Rik Protein, G protein-coupled receptor 62 Protein, GPR62 Protein, Gpr62 Protein
- Background
- Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways (PubMed:28827538). Has spontaneous activity for beta-arrestin recruitment (PubMed:28827538). Shows a reciprocal modulation of signaling functions with the melatonin receptor MTNR1B most likely through receptor heteromerization (PubMed:28827538).[UniProtKB/Swiss-Prot Function]
- Molecular Weight
- The human full length GPR62 protein has a MW of 37.6kDa
- UniProt
- Q9BZJ7
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