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GPR50 Protein

GPR50 Origin: Human Host: Mammalian Cells Synthetic Nanodisc
Catalog No. ABIN7538278
  • Target See all GPR50 Proteins
    GPR50 (G Protein-Coupled Receptor 50 (GPR50))
    Protein Type
    Synthetic Nanodisc
    Origin
    • 3
    • 1
    Human
    Source
    • 2
    • 2
    Mammalian Cells
    Purpose
    Human MTR1L full length protein-synthetic nanodisc
    Characteristics
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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    Discover our top product GPR50 Protein
  • Comment

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    GPR50 (G Protein-Coupled Receptor 50 (GPR50))
    Alternative Name
    MTR1L (GPR50 Products)
    Synonyms
    H9 Protein, Mel1c Protein, G protein-coupled receptor 50 Protein, G-protein-coupled receptor 50 Protein, GPR50 Protein, Gpr50 Protein
    Background
    This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010]
    Molecular Weight
    The human full length MTR1L protein has a MW of 67.4kDa
    UniProt
    Q13585
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