GPR50 Protein
GPR50
Origin: Human
Host: Mammalian Cells
Synthetic Nanodisc
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- Target See all GPR50 Proteins
- GPR50 (G Protein-Coupled Receptor 50 (GPR50))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- Mammalian Cells
- Purpose
- Human MTR1L full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product GPR50 Protein
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G Protein-Coupled Receptor 50 (GPR50) (AA 1-617) protein (GST tag)
GPR50 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- GPR50 (G Protein-Coupled Receptor 50 (GPR50))
- Alternative Name
- MTR1L (GPR50 Products)
- Synonyms
- H9 Protein, Mel1c Protein, G protein-coupled receptor 50 Protein, G-protein-coupled receptor 50 Protein, GPR50 Protein, Gpr50 Protein
- Background
- This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010]
- Molecular Weight
- The human full length MTR1L protein has a MW of 67.4kDa
- UniProt
- Q13585
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