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GPR157 Protein

GPR175 Origin: Human Host: Mammalian Cells Synthetic Nanodisc
Catalog No. ABIN7538257
  • Target See all GPR157 (GPR175) Proteins
    GPR157 (GPR175) (G Protein-Coupled Receptor 157 (GPR175))
    Protein Type
    Synthetic Nanodisc
    Origin
    • 4
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    Mammalian Cells
    Purpose
    Human GPR157 full length protein-synthetic nanodisc
    Characteristics
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product GPR175 Protein
  • Comment

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    GPR157 (GPR175) (G Protein-Coupled Receptor 157 (GPR175))
    Alternative Name
    GPR157 (GPR175 Products)
    Synonyms
    zgc:112049 Protein, F730108M23Rik Protein, G protein-coupled receptor 157 Protein, gpr157 Protein, GPR157 Protein, Gpr157 Protein
    Background
    Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger.[UniProtKB/Swiss-Prot Function]
    Molecular Weight
    The human full length GP157 protein has a MW of 36.6kDa
    UniProt
    Q5UAW9
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