G Protein-Coupled Receptor 12 Protein (GPR12)
GPR12
Origin: Human
Host: Mammalian Cells
Synthetic Nanodisc
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- Target See all G Protein-Coupled Receptor 12 (GPR12) Proteins
- G Protein-Coupled Receptor 12 (GPR12)
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- Mammalian Cells
- Purpose
- Human GPR12 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product GPR12 Protein
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G Protein-Coupled Receptor 12 (GPR12) (AA 1-334) protein (GST tag)
GPR12 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- G Protein-Coupled Receptor 12 (GPR12)
- Alternative Name
- GPR12 (GPR12 Products)
- Synonyms
- GPCR12 Protein, GPCR21 Protein, Gpcr12 Protein, Gpcr01 Protein, Gpcr20 Protein, Gpcr21 Protein, G protein-coupled receptor 12 Protein, G-protein coupled receptor 12 Protein, GPR12 Protein, Gpr12 Protein
- Background
- Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production.[UniProtKB/Swiss-Prot Function]
- Molecular Weight
- The human full length GPR12 protein has a MW of 36.7kDa
- UniProt
- P47775
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