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GPR107 Protein

GPR107 Origin: Human Host: Mammalian Cells Synthetic Nanodisc
Catalog No. ABIN7538252
  • Target See all GPR107 products
    GPR107 (G Protein-Coupled Receptor 107 (GPR107))
    Protein Type
    Synthetic Nanodisc
    Origin
    Human
    Source
    Mammalian Cells
    Purpose
    Human GP107 full length protein-synthetic nanodisc
    Characteristics
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • Comment

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    GPR107 (G Protein-Coupled Receptor 107 (GPR107))
    Alternative Name
    GP107 (GPR107 Products)
    Synonyms
    wu:fi85e04 Protein, zgc:153685 Protein, MGC166006 Protein, GCDRP Protein, LUSTR1 Protein, RP11-88G17 Protein, bA138E2.2 Protein, 9930033D15Rik Protein, AI790205 Protein, C530034M11 Protein, mKIAA1624 Protein, G protein-coupled receptor 107 Protein, G protein-coupled receptor 107 S homeolog Protein, Gpr107 Protein, GPR107 Protein, gpr107.S Protein, gpr107 Protein
    Background
    Has been proposed to act as a receptor for neuronostatin, a peptide derived from the somatostatin/SST precursor (PubMed:22933024). Involved in blood sugar regulation through the induction of glucagon in response to low glucose (By similarity).[UniProtKB/Swiss-Prot Function]
    Molecular Weight
    The human full length GP107 protein has a MW of 67kDa
    UniProt
    Q5VW38
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