FZD9 Protein
FZD9
Origin: Human
Host: Mammalian Cells
Synthetic Nanodisc
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- Target See all FZD9 Proteins
- FZD9 (Frizzled Family Receptor 9 (FZD9))
- Protein Type
- Synthetic Nanodisc
- Origin
- Human
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Source
- Mammalian Cells
- Purpose
- Human FZD9 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product FZD9 Protein
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- FZD9 (Frizzled Family Receptor 9 (FZD9))
- Alternative Name
- FZD9 (FZD9 Products)
- Synonyms
- CD349 Protein, FZD3 Protein, mfz9 Protein, Fz-9 Protein, cFz-9 Protein, fz11 Protein, fzd9 Protein, fzx Protein, hm:zehl0603 Protein, zehl0603 Protein, zg11 Protein, frizzled class receptor 9 Protein, frizzled class receptor 9a Protein, frizzled class receptor 9b Protein, FZD9 Protein, Fzd9 Protein, fzd9a Protein, fzd9b Protein
- Background
- Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney. [provided by RefSeq, Jul 2008]
- Molecular Weight
- The human full length FZD9 protein has a MW of 64.5kDa
- UniProt
- O00144
- Pathways
- WNT Signaling
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