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FPR3 Protein

FPR3 Origin: Human Host: Mammalian Cells Synthetic Nanodisc
Catalog No. ABIN7538240
  • Target See all FPR3 Proteins
    FPR3 (Formyl Peptide Receptor 3 (FPR3))
    Protein Type
    Synthetic Nanodisc
    Origin
    • 3
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    Mammalian Cells
    Purpose
    Human FPR3 full length protein-synthetic nanodisc
    Characteristics
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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    Discover our top product FPR3 Protein
  • Comment

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    FPR3 (Formyl Peptide Receptor 3 (FPR3))
    Alternative Name
    FPR3 (FPR3 Products)
    Synonyms
    RGD1566044 Protein, FML2_HUMAN Protein, FMLPY Protein, FPRH1 Protein, FPRH2 Protein, FPRL2 Protein, RMLP-R-I Protein, ALX Protein, Fpr-rs1 Protein, Fpr-s1 Protein, Fprl1 Protein, LXA4-R Protein, Lxa4r Protein, FMLP-R-II Protein, formyl peptide receptor 3 Protein, Fpr3 Protein, FPR3 Protein
    Background
    Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.[UniProtKB/Swiss-Prot Function]
    Molecular Weight
    The human full length FPR3 protein has a MW of 40kDa
    UniProt
    P25089
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