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FPR3 Protein

FPR3 Origin: Human Host: Mammalian Cells Synthetic Nanodisc
Catalog No. ABIN7538240
  • Target See all FPR3 Proteins
    FPR3 (Formyl Peptide Receptor 3 (FPR3))
    Protein Type
    Synthetic Nanodisc
    Origin
    • 3
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    Mammalian Cells
    Purpose
    Human FPR3 full length protein-synthetic nanodisc
    Characteristics
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product FPR3 Protein
  • Comment

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    FPR3 (Formyl Peptide Receptor 3 (FPR3))
    Alternative Name
    FPR3 (FPR3 Products)
    Synonyms
    RGD1566044 Protein, FML2_HUMAN Protein, FMLPY Protein, FPRH1 Protein, FPRH2 Protein, FPRL2 Protein, RMLP-R-I Protein, ALX Protein, Fpr-rs1 Protein, Fpr-s1 Protein, Fprl1 Protein, LXA4-R Protein, Lxa4r Protein, FMLP-R-II Protein, formyl peptide receptor 3 Protein, Fpr3 Protein, FPR3 Protein
    Background
    Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.[UniProtKB/Swiss-Prot Function]
    Molecular Weight
    The human full length FPR3 protein has a MW of 40kDa
    UniProt
    P25089
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