FPR3 Protein
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- Target See all FPR3 Proteins
- FPR3 (Formyl Peptide Receptor 3 (FPR3))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- Mammalian Cells
- Purpose
- Human FPR3 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product FPR3 Protein
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- FPR3 (Formyl Peptide Receptor 3 (FPR3))
- Alternative Name
- FPR3 (FPR3 Products)
- Synonyms
- RGD1566044 Protein, FML2_HUMAN Protein, FMLPY Protein, FPRH1 Protein, FPRH2 Protein, FPRL2 Protein, RMLP-R-I Protein, ALX Protein, Fpr-rs1 Protein, Fpr-s1 Protein, Fprl1 Protein, LXA4-R Protein, Lxa4r Protein, FMLP-R-II Protein, formyl peptide receptor 3 Protein, Fpr3 Protein, FPR3 Protein
- Background
- Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.[UniProtKB/Swiss-Prot Function]
- Molecular Weight
- The human full length FPR3 protein has a MW of 40kDa
- UniProt
- P25089
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