FCN1 Protein (AA 30-326) (His tag)
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- Target See all FCN1 Proteins
- FCN1 (Ficolin (Collagen/fibrinogen Domain Containing) 1 (FCN1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 30-326
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Origin
- Human
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Source
- Mammalian Cells
- Purification tag / Conjugate
- This FCN1 protein is labelled with His tag.
- Purpose
- Recombinant human FCN1 Protein with C-terminal 6xHis tag
- Specificity
- FCN1 (Ala30-Ala326) 6xHis tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- FCN1 (Ficolin (Collagen/fibrinogen Domain Containing) 1 (FCN1))
- Alternative Name
- FCN1 (FCN1 Products)
- Synonyms
- FCNM Protein, FCNB Protein, FCN2 Protein, FCN1 Protein, ficolin 1 Protein, ficolin (collagen/fibrinogen domain containing) 1 Protein, ficolin-1 Protein, FCN1 Protein, Fcn1 Protein, LOC100069029 Protein
- Background
- The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity. [provided by RefSeq, Jul 2008]
- Molecular Weight
- predicted molecular mass of 32.8 kDa after removal of the signal peptide. The apparent molecular mass of FCN1-His is 25-35 kDa due to glycosylation.
- UniProt
- O00602
- Pathways
- Complement System
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