EPH Receptor A2 Protein (EPHA2) (AA 26-535) (His tag)

Catalog No. ABIN7538224

Product Details

Target: EPH Receptor A2 (EPHA2)

Protein Type: Recombinant

Protein Characteristics: AA 26-535

Origin: Mouse

Source: Mammalian Cells

Purification tag / Conjugate: This EPH Receptor A2 protein is labelled with His tag.

Purpose: Recombinant mouse EPHA2 protein with C-terminal 6xHis tag

Specificity: Mouse EPHA2 (Lys26-Asn535) 6xHis tag

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Purity: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: EPH Receptor A2 (EPHA2)

Alternative Name: EPHA2 (EPHA2 Products)

Synonyms: ARCC2 Protein, CTPA Protein, CTPP1 Protein, CTRCT6 Protein, ECK Protein, epha2 Protein, MGC89505 Protein, AW545284 Protein, Eck Protein, Myk2 Protein, Sek-2 Protein, Sek2 Protein, id:ibd5152 Protein, rtk6 Protein, G42 Protein, XE10 Protein, epha2-A Protein, EPH receptor A2 Protein, Eph receptor A2 Protein, epoxide hydrolase Protein, eph receptor A2 a Protein, EPH receptor A2 L homeolog Protein, EPHA2 Protein, Epha2 Protein, epha2 Protein, ephA2 Protein, epha2a Protein, epha2.L Protein

Background: Predicted to enable growth factor binding activity and transmembrane-ephrin receptor activity. Involved in several processes, including animal organ development, osteoblast differentiation, and regulation of blood vessel endothelial cell migration. Acts upstream of or within several processes, including blood vessel morphogenesis, nervous system development, and notochord development. Located in cell surface. Is expressed in several structures, including alimentary system, branchial arch, central nervous system, endometrium, and limb. Used to study cataract 6 multiple types. Human ortholog(s) of this gene implicated in cataract 6 multiple types. Orthologous to human EPHA2 (EPH receptor A2). [provided by Alliance of Genome Resources, Apr 2022]

Molecular Weight: predicted molecular mass of 57.4 kDa after removal of the signal peptide. The apparent molecular mass of mEPHA2-His is 55-70 kDa due to glycosylation.

UniProt: Q03145

Pathways: RTK Signaling