DRD5 Protein
DRD5
Origin: Human
Host: Mammalian Cells
Synthetic Nanodisc
-
- Target See all DRD5 Proteins
- DRD5 (Dopamine Receptor D5 (DRD5))
- Protein Type
- Synthetic Nanodisc
-
Origin
- Human
-
Source
- Mammalian Cells
- Purpose
- Human DRD5 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product DRD5 Protein
-
-
- Comment
-
Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
-
- Target
- DRD5 (Dopamine Receptor D5 (DRD5))
- Alternative Name
- DRD5 (DRD5 Products)
- Synonyms
- DRD5 Protein, DBDR Protein, DRD1B Protein, DRD1L2 Protein, D1B Protein, D5R Protein, Drd-5 Protein, Drd1b Protein, Gpcr1 Protein, dopamine receptor D5 Protein, DRD5 Protein, Drd5 Protein
- Background
- This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. [provided by RefSeq, Jul 2008]
- Molecular Weight
- The human full length DRD5 protein has a MW of 53kDa
- UniProt
- P21918
- Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
-
You are here:
