Dopamine Receptor d1 Protein
DRD1
Origin: Human
Host: Mammalian Cells
Synthetic Nanodisc
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- Target See all Dopamine Receptor d1 (DRD1) Proteins
- Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- Mammalian Cells
- Purpose
- Human DRD1 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product DRD1 Protein
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))
- Alternative Name
- DRD1 (DRD1 Products)
- Synonyms
- DRD1 Protein, Dop1 Protein, D1A Protein, DADR Protein, DRD1A Protein, drd1 Protein, C030036C15Rik Protein, Drd-1 Protein, Drd1 Protein, Gpcr15 Protein, D1a Protein, Drd1a Protein, dopamine receptor D1 Protein, dopamine receptor, D1 Protein, dopamine receptor D1b Protein, DRD1 Protein, Dop1 Protein, drd1b Protein, Drd1 Protein
- Background
- This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]
- Molecular Weight
- The human full length DRD1 protein has a MW of 49.3kDa
- UniProt
- P21728
- Pathways
- cAMP Metabolic Process, Inositol Metabolic Process, Protein targeting to Nucleus, Feeding Behaviour, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
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