CRLF2 Protein (AA 23-231) (His tag)
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- Target See all CRLF2 Proteins
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-231
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Origin
- Human
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Source
- Mammalian Cells
- Purification tag / Conjugate
- This CRLF2 protein is labelled with His tag.
- Purpose
- Recombinant Human CRLF2 Protein with C-terminal 6XHis tag
- Specificity
- CRLF2 (Gln23-Lys231) 6xHis tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CRLF2 Protein
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Cytokine Receptor-Like Factor 2 (CRLF2) protein (Fc Tag)
CRLF2 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Cytokine Receptor-Like Factor 2 (CRLF2) (AA 25-231) protein (His tag)CRLF2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-231) protein (His tag)CRLF2 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Cytokine Receptor-Like Factor 2 (CRLF2) (AA 25-231) (Active) protein (Fc Tag)CRLF2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Cytokine Receptor-Like Factor 2 (CRLF2) (Active) protein (Fc Tag)CRLF2 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-132) protein (GST tag)CRLF2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cytokine Receptor-Like Factor 2 (CRLF2) protein (His tag)CRLF2 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Cytokine Receptor-Like Factor 2 (CRLF2) protein (Fc Tag)CRLF2 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
- Alternative Name
- CRLF2 (CRLF2 Products)
- Synonyms
- CRLF2 Protein, CRL2 Protein, CRLF2Y Protein, TSLPR Protein, CRLM2 Protein, Ly114 Protein, Tpte2 Protein, Tslpr Protein, Crl2 Protein, cytokine receptor like factor 2 Protein, cytokine receptor-like factor 2 Protein, CRLF2 Protein, Crlf2 Protein
- Background
- This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]
- Molecular Weight
- predicted molecular mass of 25.0 kDa after removal of the signal peptide. The apparent molecular mass of CRLF2-His is 25-55 kDa due to glycosylation.
- UniProt
- Q9HC73
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