Contactin 1 Protein (CNTN1)
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- Target See all Contactin 1 (CNTN1) Proteins
- Contactin 1 (CNTN1)
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- Mammalian Cells
- Purpose
- Human GP135 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product CNTN1 Protein
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Contactin 1 (CNTN1) protein (His tag)
CNTN1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Contactin 1 (CNTN1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CNTN1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- Contactin 1 (CNTN1)
- Alternative Name
- GP135 (CNTN1 Products)
- Synonyms
- F3 Protein, GP135 Protein, AW495098 Protein, CNTN Protein, F3cam Protein, F3/F11 Protein, cntn-A Protein, F11 Protein, CNTN1 Protein, cntn1 Protein, contactin 1 Protein, contactin 1 L homeolog Protein, contactin 1a Protein, CNTN1 Protein, Cntn1 Protein, cntn1.L Protein, cntn1a Protein
- Background
- Orphan receptor. Has spontaneous activity for beta-arrestin recruitment (PubMed:28827538). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (PubMed:28827538).[UniProtKB/Swiss-Prot Function]
- Molecular Weight
- The human full length GP135 protein has a MW of 51.7kDa
- UniProt
- Q8IZ08
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