CCL24 Protein (Fc Tag)

Catalog No. ABIN7538180

Product Details

Target: CCL24 (Chemokine (C-C Motif) Ligand 24 (CCL24))

Protein Type: Recombinant

Origin: Human

Source: Mammalian Cells

Purification tag / Conjugate: This CCL24 protein is labelled with Fc Tag.

Purpose: Recombinant human CCL24 Protein with N-terminal human Fc tag

Specificity: HFc (Glu99-Ala330) CCL24 (Val27-Cys119)

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: CCL24 (Chemokine (C-C Motif) Ligand 24 (CCL24))

Alternative Name: CCL24 (CCL24 Products)

Synonyms: Ckb-6 Protein, MPIF-2 Protein, MPIF2 Protein, SCYA24 Protein, CKb-6 Protein, Scya24 Protein, C-C motif chemokine ligand 24 Protein, chemokine (C-C motif) ligand 24 Protein, CCL24 Protein, Ccl24 Protein

Background: This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. This protein also has antimicrobial activity, displaying an antibacterial effect on S. pneumoniae, S. aureus, Non-typeable H. influenzae, and P. aeruginosa. Finally, the protein is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. [provided by RefSeq, Jul 2020]

Molecular Weight: predicted molecular mass of 36.6 kDa after removal of the signal peptide. The apparent molecular mass of hFc-CCL24 is 35-55 kDa due to glycosylation.

UniProt: O00175

Pathways: Regulation of Actin Filament Polymerization