XCR1 Protein (AA 1-31) (Fc Tag)
XCR1
Origin: Human
Host: Mammalian Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Target See all XCR1 Proteins
- XCR1 (Chemokine (C Motif) Receptor 1 (XCR1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-31
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Origin
- Human
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Source
- Mammalian Cells
- Purification tag / Conjugate
- This XCR1 protein is labelled with Fc Tag.
- Purpose
- Recombinant human XCR1 Protein with C-terminal human Fc tag
- Specificity
- XCR1 (Met1-Thr31) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- XCR1 (Chemokine (C Motif) Receptor 1 (XCR1))
- Alternative Name
- XCR1 (XCR1 Products)
- Synonyms
- CCXCR1-L Protein, XCR1 Protein, CCXCR1 Protein, GPR5 Protein, Ccxcr1 Protein, Gpr5 Protein, mXcr1 Protein, X-C motif chemokine receptor 1 Protein, chemokine (C motif) receptor 1a, duplicate 1 Protein, chemokine (C motif) receptor 1 Protein, XCR1 Protein, xcr1a.1 Protein, Xcr1 Protein
- Background
- The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains. The encoded protein transduces a signal by increasing the intracellular calcium ion level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Some studies have implicated a cluster of genes at 3p21.31, including this gene, as associated with COVID-19 risk. The encoded protein may also play a role in cell proliferation and migration in several types of cancer. [provided by RefSeq, Jan 2023]
- Molecular Weight
- predicted molecular mass of 29.7 kDa after removal of the signal peptide. The apparent molecular mass of XCR1-hFc is 35-55 kDa due to glycosylation.
- UniProt
- P46094
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