CD70 Protein (Fc Tag)
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- Target See all CD70 Proteins
- CD70 (CD70 Molecule (CD70))
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- Mammalian Cells
- Purification tag / Conjugate
- This CD70 protein is labelled with Fc Tag.
- Purpose
- Recombinant mouse CD70 protein with N-terminal human Fc tag
- Specificity
- HFc (Glu99-Ala330) Mouse CD70 (Ser45-Pro195)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CD70 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CD70 (CD70 Molecule (CD70))
- Alternative Name
- CD70 (CD70 Products)
- Synonyms
- CD27LG Protein, Cd27l Protein, Tnfsf7 Protein, CD27L Protein, TNFSF7 Protein, CD70 antigen Protein, CD70 molecule Protein, Cd70 molecule Protein, Cd70 Protein, CD70 Protein
- Background
- Predicted to enable cytokine activity and protease binding activity. Predicted to be involved in several processes, including B cell proliferation, T cell mediated immunity, and extrinsic apoptotic signaling pathway. Predicted to be located in extracellular space and membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in Meckel's cartilage, hip, and skeleton. Human ortholog(s) of this gene implicated in lymphoproliferative syndrome. Orthologous to human CD70 (CD70 Molecule). [provided by Alliance of Genome Resources, Apr 2022]
- Molecular Weight
- predicted molecular mass of 42.8 kDa after removal of the signal peptide. The apparent molecular mass of hFc-mCD70 is 35-70 kDa due to glycosylation.
- UniProt
- O55237
- Pathways
- Cancer Immune Checkpoints
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