CALCRL Protein (AA 23-140) (mFc Tag)
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- Target See all CALCRL Proteins
- CALCRL (Calcitonin Receptor-Like (CALCRL))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-140
- Origin
- Human
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Source
- Mammalian Cells
- Purification tag / Conjugate
- This CALCRL protein is labelled with mFc Tag.
- Purpose
- Recombinant human CGRPR Protein with C-terminal mouse Fc tag
- Specificity
- CGRPR (Glu23-Asn140) mFc (Pro99-Lys330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CALCRL Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CALCRL (Calcitonin Receptor-Like (CALCRL))
- Alternative Name
- CGRPR (CALCRL Products)
- Synonyms
- CALCRL Protein, CGRPR Protein, CRLR Protein, AV071593 Protein, CLR Protein, Crlr Protein, RATCRLR Protein, RNCLR Protein, calcitonin receptor like receptor Protein, calcitonin receptor-like Protein, calcitonin receptor like receptor L homeolog Protein, CALCRL Protein, LOC100168906 Protein, calcrl Protein, Calcrl Protein, calcrl.L Protein
- Background
- Enables adrenomedullin binding activity, adrenomedullin receptor activity, and calcitonin gene-related peptide receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway, cellular response to sucrose stimulus, and receptor internalization. Located in endoplasmic reticulum, endosome, and lysosome. Part of CGRP receptor complex and adrenomedullin receptor complex. Colocalizes with plasma membrane. Implicated in hereditary lymphedema. [provided by Alliance of Genome Resources, Apr 2022]
- Molecular Weight
- predicted molecular mass of 40.0 kDa after removal of the signal peptide. The apparent molecular mass of CGRPR-mFc is 35-70 kDa due to glycosylation.
- UniProt
- Q16602
- Pathways
- cAMP Metabolic Process
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