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CALCRL Protein (AA 23-140) (Fc Tag)

CALCRL Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7538151
  • Target See all CALCRL Proteins
    CALCRL (Calcitonin Receptor-Like (CALCRL))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 23-140
    Origin
    • 8
    • 2
    Human
    Source
    • 4
    • 3
    • 3
    Mammalian Cells
    Purification tag / Conjugate
    This CALCRL protein is labelled with Fc Tag.
    Purpose
    Recombinant human CGRPR Protein with C-terminal human Fc tag
    Specificity
    CGRPR (Glu23-Asn140) hFc (Glu99-Ala330)
    Characteristics
    Extracellular Domain Protein
    Purification
    Purified from cell culture supernatant by affinity chromatography
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product CALCRL Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    CALCRL (Calcitonin Receptor-Like (CALCRL))
    Alternative Name
    CGRPR (CALCRL Products)
    Synonyms
    CALCRL Protein, CGRPR Protein, CRLR Protein, AV071593 Protein, CLR Protein, Crlr Protein, RATCRLR Protein, RNCLR Protein, calcitonin receptor like receptor Protein, calcitonin receptor-like Protein, calcitonin receptor like receptor L homeolog Protein, CALCRL Protein, LOC100168906 Protein, calcrl Protein, Calcrl Protein, calcrl.L Protein
    Background
    Enables adrenomedullin binding activity, adrenomedullin receptor activity, and calcitonin gene-related peptide receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway, cellular response to sucrose stimulus, and receptor internalization. Located in endoplasmic reticulum, endosome, and lysosome. Part of CGRP receptor complex and adrenomedullin receptor complex. Colocalizes with plasma membrane. Implicated in hereditary lymphedema. [provided by Alliance of Genome Resources, Apr 2022]
    Molecular Weight
    predicted molecular mass of 39.9 kDa after removal of the signal peptide. The apparent molecular mass of CGRPR-hFc is 35-70 kDa due to glycosylation.
    UniProt
    Q16602
    Pathways
    cAMP Metabolic Process
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