MERTK Protein (AA 21-505) (His tag)
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- Target See all MERTK Proteins
- MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-505
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Origin
- Human
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Source
- Mammalian Cells
- Purification tag / Conjugate
- This MERTK protein is labelled with His tag.
- Purpose
- Recombinant human MERTK Protein with C-terminal 10xHis tag
- Specificity
- MERTK (Ala21-Ile505) 10xHis tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product MERTK Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))
- Alternative Name
- MERTK (MERTK Products)
- Synonyms
- MER Protein, RP38 Protein, c-mer Protein, Eyk Protein, Mer Protein, Nyk Protein, nmf12 Protein, rdy Protein, C-EYK Protein, MERTK Protein, DKFZp469D2215 Protein, si:ch1073-268l12.2 Protein, MER proto-oncogene, tyrosine kinase Protein, c-mer proto-oncogene tyrosine kinase Protein, c-mer proto-oncogene tyrosine kinase a Protein, MERTK Protein, Mertk Protein, mertka Protein
- Background
- This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008]
- Molecular Weight
- predicted molecular mass of 54.0 kDa after removal of the signal peptide.
- UniProt
- Q12866
- Pathways
- RTK Signaling
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