BAMBI Protein (AA 27-152) (Fc Tag)

Catalog No. ABIN7538144

Product Details

Target: BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))

Protein Type: Recombinant

Protein Characteristics: AA 27-152

Origin: Human

Source: Mammalian Cells

Purification tag / Conjugate: This BAMBI protein is labelled with Fc Tag.

Purpose: Recombinant human BAMBI Protein with C-terminal human Fc tag

Specificity: BAMBI (Glu27-Ala152) hFc (Glu99-Ala330)

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))

Alternative Name: BAMBI (BAMBI Products)

Synonyms: NMA Protein, bambi Protein, nma Protein, BAMBI Protein, Zfnma Protein, cb998 Protein, fc44c12 Protein, id:ibd5020 Protein, wu:fc44c12 Protein, wu:fe01e03 Protein, 2610003H06Rik Protein, bambi-A Protein, zgc:91871 Protein, BMP and activin membrane bound inhibitor Protein, BMP and activin membrane-bound inhibitor homolog Protein, BMP and activin membrane-bound inhibitor Protein, BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a Protein, BMP and activin membrane-bound inhibitor L homeolog Protein, BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b Protein, BAMBI Protein, bambi Protein, bambia Protein, Bambi Protein, LOC724378 Protein, LOC100647353 Protein, bambi.L Protein, bambib Protein

Background: This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 2008]

Molecular Weight: predicted molecular mass of 40.1 kDa after removal of the signal peptide. The apparent molecular mass of BAMBI-hFc is 55-70 kDa due to glycosylation.

UniProt: Q13145