Apelin Protein (APLN) (AA 23-77) (Fc Tag)
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- Target See all Apelin (APLN) Proteins
- Apelin (APLN)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-77
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Origin
- Human
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Source
- Mammalian Cells
- Purification tag / Conjugate
- This Apelin protein is labelled with Fc Tag.
- Purpose
- Recombinant human APLN Protein with C-terminal human Fc tag
- Specificity
- APLN (Gly23-Phe77) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product APLN Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- Apelin (APLN)
- Alternative Name
- APLN (APLN Products)
- Synonyms
- APLN Protein, Xapelin Protein, xnpep2 Protein, preproapelin Protein, 6030430G11Rik Protein, Apel Protein, APEL Protein, XNPEP2 Protein, apelin Protein, apelin S homeolog Protein, apln Protein, APLN Protein, apln.S Protein, Apln Protein
- Background
- This gene encodes a peptide that functions as an endogenous ligand for the G-protein coupled apelin receptor. The encoded preproprotein is proteolytically processed into biologically active C-terminal peptide fragments. These peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1. [provided by RefSeq, Feb 2016]
- Molecular Weight
- predicted molecular mass of 32.3 kDa after removal of the signal peptide. The apparent molecular mass of APLN-hFc is 25-55 kDa due to glycosylation.
- UniProt
- Q9ULZ1
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Feeding Behaviour
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