ADGRE5 (AA 21-552) protein (His tag)
Origin: Human
Host: Mammalian Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
1 image
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- Target
- ADGRE5
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-552
- Origin
- Human
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Source
- Mammalian Cells
- Purification tag / Conjugate
- His tag
- Purpose
- Recombinant human ADGRE5 Protein with C-terminal 6xHis tag
- Specificity
- ADGRE5 (Gln21-Arg552) 6xHis tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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ADGRE5 protein
Origin: Human Host: HEK-293 Cells Synthetic Nanodisc
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- ADGRE5
- Synonyms
- TM7LN1 Protein, adhesion G protein-coupled receptor E5 Protein, ADGRE5 Protein
- Background
- This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011]
- Molecular Weight
- predicted molecular mass of 58.9 kDa after removal of the signal peptide.
- UniProt
- P48960
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