LUM Protein (His tag)
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- Target See all LUM Proteins
- LUM (Lumican (LUM))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LUM protein is labelled with His tag.
- Purpose
- Recombinant Human Lumican/LUM Protein
- Sequence
- QYYDYDFPLS IYGQSSPNCA PECNCPESYP SAMYCDELKL KSVPMVPPGI KYLYLRNNQI DHIDEKAFEN VTDLQWLILD HNLLENSKIK GRVFSKLKQL KKLHINHNNL TESVGPLPKS LEDLQLTHNK ITKLGSFEGL VNLTFIHLQH NRLKEDAVSA AFKGLKSLEY LDLSFNQIAR LPSGLPVSLL TLYLDNNKIS NIPDEYFKRF NALQYLRLSH NELADSGIPG NSFNVSSLVE LDLSYNKLKN IPTVNENLEN YYLEVNQLEK FDIKSFCKIL GPLSYSKIKH LRLDGNRISE TSLPPDMYEC LRVANEVTLN
- Specificity
- Gln19-Asn338
- Purity
- > 95 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- < 0.1 EU/μg of the protein by LAL method.
- Top Product
- Discover our top product LUM Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- Target
- LUM (Lumican (LUM))
- Alternative Name
- Lumican/LUM (LUM Products)
- Synonyms
- MGC64527 Protein, zgc:86661 Protein, ldc Protein, slrr2d Protein, DKFZp468L1116 Protein, LDC Protein, SLRR2D Protein, Ldc Protein, lumican Protein, lumican L homeolog Protein, LUM Protein, lum.L Protein, lum Protein, CpipJ_CPIJ010209 Protein, Lum Protein
- Background
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Description: Lumican is a member of the family of small leucine-rich repeat proteoglycans (SLRPs) and the class II subfamily .which is a major component of the cornea, dermal, and muscle connective tissues. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican regulates collagenous matrix assembly as a keratan sulfate proteoglycan in the cornea and is also present in the connective tissues of other organs and embryonic corneal stroma as a glycoprotein. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. Lumican's over-expression has been reported in carcinoid tumor, breast, colorectal, neuroendocrine, uterine cervical and pancreatic cancers
Name: LDC, SLRR2D,LUM,SLRR2D,lumican
- Gene ID
- 4060
- UniProt
- P51884
- Pathways
- Glycosaminoglycan Metabolic Process
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