FKBP1A Protein
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- Target See all FKBP1A Proteins
- FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Human FKBP1A/FKBP12 Protein
- Sequence
- MGVQVETISP GDGRTFPKRG QTCVVHYTGM LEDGKKFDSS RDRNKPFKFM LGKQEVIRGW EEGVAQMSVG QRAKLTISPD YAYGATGHPG IIPPHATLVF DVELLKLE
- Specificity
- Met1-Glu108
- Purity
- > 90 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- < 0.1 EU/μg of the protein by LAL method.
- Top Product
- Discover our top product FKBP1A Protein
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FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 1-108) protein (GST tag)
FKBP1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 1-108) protein (His tag)FKBP1A Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 1-108) protein (His tag)FKBP1A Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 2-103), (partial) protein (GST tag)FKBP1A Origin: Human Host: Escherichia coli (E. coli) Recombinant 95 % ELISA
FK506 Binding Protein 1A, 12kDa (FKBP1A) (Transcript Variant 12B) protein (Myc-DYKDDDDK Tag)FKBP1A Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH 8.0.
- Storage
- -20 °C,-80 °C
- Storage Comment
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- Target
- FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
- Alternative Name
- FKBP1A/FKBP12 (FKBP1A Products)
- Background
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Description: The protein is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor.
Name: FKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE,FKBP1A,FKBP-1A,FKBP1,FKBP12,PKC12,PKCI2,PPIASE
- Gene ID
- 2280
- UniProt
- P62942
- Pathways
- Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
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