FGFR4 Protein (His tag)

Catalog No. ABIN7535788

Product Details

Target: FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This FGFR4 protein is labelled with His tag.

Purpose: Recombinant Mouse FGFR-4/CD334 Protein

Sequence: LSLEASEEME QEPCLAPILE QQEQVLTVAL GQPVRLCCGR TERGRHWYKE GSRLASAGRV RGWRGRLEIA SFLPEDAGRY LCLARGSMTV VHNLTLLMDD SLTSISNDED PKTLSSSSSG HVYPQQAPYW THPQRMEKKL HAVPAGNTVK FRCPAAGNPM PTIHWLKDGQ AFHGENRIGG IRLRHQHWSL VMESVVPSDR GTYTCLVENS LGSIRYSYLL DVLERSPHRP ILQAGLPANT TAVVGSDVEL LCKVYSDAQP HIQWLKHVVI NGSSFGADGF PYVQVLKTTD INSSEVEVLY LRNVSAEDAG EYTCLAGNSI GLSYQSAWLT VLPEEDLTWT TATPEARYTD

Specificity: Leu17-Asp366

Purity: > 95 % by SDS-PAGE.

Sterility: 0.22 μm filtered

Endotoxin Level: < 0.1 EU/μg of the protein by LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Storage: -20 °C,-80 °C

Storage Comment: Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Target Details

Target: FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

Alternative Name: FGFR-4/CD334 (FGFR4 Products)

Synonyms: FGFR4 Protein, XFGFR-4 Protein, XFGFR-4a Protein, cd334 Protein, fgfr-4 Protein, jtk2 Protein, tkf Protein, xfgfr4 Protein, CD334 Protein, JTK2 Protein, TKF Protein, Fgfr-4 Protein, etID309818.21 Protein, wu:fc13h10 Protein, zgc:111935 Protein, fgfr-4c Protein, fgfr4 Protein, fibroblast growth factor receptor 4 Protein, fibroblast growth factor receptor 4 S homeolog Protein, FGFR4 Protein, fgfr4 Protein, Fgfr4 Protein, fgfr4.S Protein

Background:

Description: The protein is a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described.

Name: Fgfr-4,FGFR4,CD334,JTK2,MGC20292,TKF,FGFR4,Fgfr-4,FGFR4,CD334,JTK2,MGC20292,TKF,FGFR4

Gene ID: 14186

UniProt: Q03142

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding