FGF6 Protein
-
- Target See all FGF6 Proteins
- FGF6 (Fibroblast Growth Factor 6 (FGF6))
- Protein Type
- Recombinant
- Biological Activity
- Active
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purpose
- Active Recombinant Human FGF-6 Protein
- Sequence
- GTRANNTLLD SRGWGTLLSR SRAGLAGEIA GVNWESGYLV GIKRQRRLYC NVGIGFHLQV LPDGRISGTH EENPYSLLEI STVERGVVSL FGVRSALFVA MNSKGRLYAT PSFQEECKFR ETLLPNNYNA YESDLYQGTY IALSKYGRVK RGSKVSPIMT VTHFLPRI
- Specificity
- Gly41-Ile208
- Purity
- > 95 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized Human FGF6 Protein at 1 μg/mL (100 μL/well) can bind FGFR4 with a linear range of 1.95-97.8 ng/mL.
- Top Product
- Discover our top product FGF6 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
-
- Target
- FGF6 (Fibroblast Growth Factor 6 (FGF6))
- Alternative Name
- FGF-6 (FGF6 Products)
- Synonyms
- FGF6 Protein, hst2 Protein, fgf-6 Protein, hbgf-6 Protein, HBGF-6 Protein, HST2 Protein, Fgf-6 Protein, HSTF-2 Protein, fgf4 Protein, fgf6 Protein, fibroblast growth factor 6 Protein, fibroblast growth factor 6a Protein, FGF6 Protein, fgf6 Protein, Fgf6 Protein, fgf6a Protein
- Background
-
Description: FGF6, also known as FGF-6, belongs to the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF6 plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis. It is also required for normal muscle regeneration. FGF6 gene displayed oncogenic transforming activity when transfected into mammalian cells.
Name: FGF6,HBGF-6,HST2
- Gene ID
- 2251
- UniProt
- P10767
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
-