EPOR Protein (His tag)
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- Target See all EPOR Proteins
- EPOR (Erythropoietin Receptor (EPOR))
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This EPOR protein is labelled with His tag.
- Purpose
- Recombinant Mouse EPO-R/Epor Protein
- Sequence
- APSPSLPDPK FESKAALLAS RGSEELLCFT QRLEDLVCFW EEAASSGMDF NYSFSYQLEG ESRKSCSLHQ APTVRGSVRF WCSLPTADTS SFVPLELQVT EASGSPRYHR IIHINEVVLL DAPAGLLARR AEEGSHVVLR WLPPPGAPMT THIRYEVDVS AGNRAGGTQR VEVLEGRTEC VLSNLRGGTR YTFAVRARMA EPSFSGFWSA WSEPASLLTA SDLDP
- Specificity
- Ala25-Pro249
- Purity
- > 97 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- < 0.1EU/μg
- Top Product
- Discover our top product EPOR Protein
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Erythropoietin Receptor (EPOR) (AA 25-138) protein (His-IF2DI Tag)
EPOR Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Erythropoietin Receptor (EPOR) (AA 31-130) protein (GST tag)EPOR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Erythropoietin Receptor (EPOR) (AA 1-508) protein (GST tag)EPOR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Erythropoietin Receptor (EPOR) (Active) protein (His tag)EPOR Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Concentration
- 0.36 mg/mL
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Target
- EPOR (Erythropoietin Receptor (EPOR))
- Alternative Name
- EPO-R/Epor (EPOR Products)
- Synonyms
- EPOR Protein, epor Protein, EPO-R Protein, erythropoietin receptor Protein, erythropoietin receptor L homeolog Protein, EPOR Protein, epor Protein, Epor Protein, epor.L Protein
- Background
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Description: Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type a... single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion.
Name: EPO-R,Epor
- Gene ID
- 13857
- UniProt
- P14753
- Pathways
- JAK-STAT Signaling
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