Clusterin Protein (CLU) (His tag)
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- Target See all Clusterin (CLU) Proteins
- Clusterin (CLU)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Clusterin protein is labelled with His tag.
- Purpose
- Recombinant Human Clusterin/Apo-J/CLU Protein
- Sequence
- DQTVSDNELQ EMSNQGSKYV NKEIQNAVNG VKQIKTLIEK TNEERKTLLS NLEEAKKKKE DALNETRESE TKLKELPGVC NETMMALWEE CKPCLKQTCM KFYARVCRSG SGLVGRQLEE FLNQSSPFYF WMNGDRIDSL LENDRQQTHM LDVMQDHFSR ASSIIDELFQ DRFFTREPQD TYHYLPFSLP HRRPHFFFPK SRIVRSLMPF SPYEPLNFHA MFQPFLEMIH EAQQAMDIHF HSPAFQHPPT EFIREGDDDR TVCREIRHNS TGCLRMKDQC DKCREILSVD CSTNNPSQAK LRRELDESLQ VAERLTRKYN ELLKSYQWKM LNTSSLLEQL NEQFNWVSRL ANLTQGEDQY YLRVTTVASH TSDSDVPSGV TEVVVKLFDS DPITVTVPVE VSRKNPKFME TVAEKALQEY RKKHREE
- Specificity
- Asp23-Arg227(βchain)&Ser228-Glu449(αchain)
- Purity
- > 85 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- < 0.1 EU/μg of the protein by LAL method.
- Top Product
- Discover our top product CLU Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- Target
- Clusterin (CLU)
- Alternative Name
- Clusterin/Apo-J/CLU (CLU Products)
- Synonyms
- LOC100136120 Protein, clu Protein, MGC53055 Protein, zgc:73352 Protein, xclu Protein, MGC89163 Protein, CLU Protein, APO-J Protein, APOJ Protein, CLI Protein, CLU1 Protein, CLU2 Protein, KUB1 Protein, NA1/NA2 Protein, SGP-2 Protein, SGP2 Protein, SP-40 Protein, TRPM-2 Protein, TRPM2 Protein, DAG Protein, RATTRPM2B Protein, SP40 Protein, TRPM2B Protein, Trpm2 Protein, Trpmb Protein, AI893575 Protein, ApoJ Protein, Cli Protein, D14Ucla3 Protein, Sgp-2 Protein, Sgp2 Protein, Sugp-2 Protein, GP80 Protein, gpIII Protein, 40 Protein, clusterin-1 Protein, clusterin L homeolog Protein, clusterin Protein, Clusterin Protein, LOC100136120 Protein, clu.L Protein, clu Protein, CLU Protein, clus Protein, Clu Protein, LOC101113728 Protein
- Background
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Description: The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.
Name: CLU,AAG4,APO-J,APOJ,CLI,CLU1,CLU2,KUB1,NA1/NA2,SGP-2,SGP2,SP-40,TRPM-2,TRPM2,clusterin,Clusterin alpha chain
- Gene ID
- 1191
- UniProt
- P10909
- Pathways
- Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
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