CCL3 Protein
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- Target See all CCL3 Proteins
- CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Yeast (Pichia pastoris)
- Purpose
- Recombinant Human CCL3/MIP-1 alpha Protein
- Sequence
- ASLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPGV IFLTKRSRQV CADPSEEWVQ KYVSDLELSA
- Specificity
- Ala23-Ala92
- Purity
- > 95 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- 601EU/μg
- Top Product
- Discover our top product CCL3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Target
- CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
- Alternative Name
- CCL3/MIP-1 alpha (CCL3 Products)
- Background
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Description: Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
Name: MIP1A, SCYA3, G0S19-1, LD78ALPHA, MIP-1-alpha,CCL3
- Gene ID
- 6348
- UniProt
- P10147
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Autophagy
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