CCL19 Protein (Fc Tag)
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- Target See all CCL19 Proteins
- CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CCL19 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human CCL19/MIP-3 beta Protein
- Sequence
- GTNDAEDCCL SVTQKPIPGY IVRNFHYLLI KDGCRVPAVV FTTLRGRQLC APPDQPWVER IIQRLQRTSA KMKRRSS
- Specificity
- Gly22-Ser98
- Purity
- > 95 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- <0.1EU/μg
- Top Product
- Discover our top product CCL19 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Target
- CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))
- Alternative Name
- CCL19/MIP-3 beta (CCL19 Products)
- Synonyms
- CKb11 Protein, ELC Protein, MIP-3b Protein, MIP3B Protein, SCYA19 Protein, CCL19 Protein, Scya19 Protein, exodus-3 Protein, C-C motif chemokine ligand 19 Protein, chemokine (C-C motif) ligand 19 Protein, CCL19 Protein, ccl19 Protein, Ccl19 Protein
- Background
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Description: May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Name: ELC, CKb11, MIP3B, MIP-3b, SCYA19,CCL19
- Gene ID
- 6363
- UniProt
- Q99731
- Pathways
- Positive Regulation of Immune Effector Process
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