CD5L Protein (His tag)
-
- Target See all CD5L Proteins
- CD5L (CD5 Molecule-Like (CD5L))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD5L protein is labelled with His tag.
- Purpose
- Recombinant Human CD5L Protein
- Sequence
- SPSGVRLVGG LHRCEGRVEV EQKGQWGTVC DDGWDIKDVA VLCRELGCGA ASGTPSGILY EPPAEKEQKV LIQSVSCTGT EDTLAQCEQE EVYDCSHDED AGASCENPES SFSPVPEGVR LADGPGHCKG RVEVKHQNQW YTVCQTGWSL RAAKVVCRQL GCGRAVLTQK RCNKHAYGRK PIWLSQMSCS GREATLQDCP SGPWGKNTCN HDEDTWVECE DPFDLRLVGG DNLCSGRLEV LHKGVWGSVC DDNWGEKEDQ VVCKQLGCGK SLSPSFRDRK CYGPGVGRIW LDNVRCSGEE QSLEQCQHRF WGFHDCTHQE DVAVICSG
- Specificity
- Ser20-Gly347
- Purity
- > 92 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- < 0.1 EU/μg of the protein by LAL method.
- Top Product
- Discover our top product CD5L Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Concentration
- 0.61 mg/mL
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
-
Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
-
- Target
- CD5L (CD5 Molecule-Like (CD5L))
- Alternative Name
- CD5L (CD5L Products)
- Synonyms
- AIM Protein, API6 Protein, PRO229 Protein, SP-ALPHA Protein, Spalpha Protein, 1/6 Protein, AAC-11 Protein, AI047839 Protein, Api6 Protein, CT2 Protein, Pdp Protein, Sp-alpha Protein, CD5L Protein, CD5 molecule like Protein, CD5 antigen-like Protein, Cd5 molecule-like Protein, CD5 molecule-like Protein, scavenger receptor cysteine-rich domain superfamily protein-like Protein, CD5L Protein, Cd5l Protein, LOC100375137 Protein
- Background
-
Description: CD5L (CD5 antigen-like), also known as Sp alpha and AIM, is a 50 kDa secreted glycoprotein that belongs to the SRCR (scavenger receptor cysteine rich) group B family of proteins. CD5L is up-regulated in macrophages at inflammatory sites. It sustains inflammatory reactions by both increasing the phagocytic capacity of macrophages and impeding the apoptosis of local macrophages, NK cells, and T cells. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram negative bacteria. In the thymic cortex, CD5L protects cortical CD4+CD8+thymocytes from apoptosis. CD5L circulates in the serum in complex with IgM.
Name: CD5L,AIM,API6,CT-2,PRO229,SP-ALPHA,Spalpha,hAIM
- Gene ID
- 922
- UniProt
- O43866
-