CEACAM3 Protein (His tag)
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- Target See all CEACAM3 Proteins
- CEACAM3 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 (CEACAM3))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CEACAM3 protein is labelled with His tag.
- Purpose
- Active Recombinant Human CEACAM3/CD66d Protein
- Sequence
- MGPPSASPHR ECIPWQGLLL TASLLNFWNP PTTAKLTIES MPLSVAEGKE VLLLVHNLPQ HLFGYSWYKG ERVDGNSLIV GYVIGTQQAT PGAAYSGRET IYTNASLLIQ NVTQNDIGFY TLQVIKSDLV NEEATGQFHV YQENAPGLPV GAVAG
- Specificity
- Met1-Gly155
- Purity
- > 92 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- < 0.1 EU/μg of the protein by LAL method.
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized Human CEACAM3 at 1μg/mL (100 μL/well) can bind CEACAM3 Mouse mAb with a linear range of 0.1-2.7 ng/mL.
- Top Product
- Discover our top product CEACAM3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- Target
- CEACAM3 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 (CEACAM3))
- Alternative Name
- CEACAM3/CD66d (CEACAM3 Products)
- Synonyms
- CD66D Protein, CEA Protein, CGM1 Protein, W264 Protein, W282 Protein, CGM4AA Protein, Cea Protein, Ceacam5 Protein, Cear Protein, Cgm1 Protein, Cgm4 Protein, RATCEAA Protein, RATCGM4AA Protein, EG384557 Protein, Psg24 Protein, cea12 Protein, carcinoembryonic antigen related cell adhesion molecule 3 Protein, carcinoembryonic antigen-related cell adhesion molecule 3 Protein, CEACAM3 Protein, Ceacam3 Protein
- Background
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Description: The protein encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described.
Name: CEACAM3,CD66D,CEA,CGM1,W264,W282
- Gene ID
- 1084
- UniProt
- P40198
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