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CA2 Protein

CA2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS-PAGE. Active
Catalog No. ABIN7533772
  • Target See all CA2 Proteins
    CA2 (Carbonic Anhydrase II (CA2))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 11
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 17
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purpose
    Active Recombinant Human Carbonic anhydrase 2 Protein
    Sequence
    SHHWGYGKHN GPEHWHKDFP IAKGERQSPV DIDTHTAKYD PSLKPLSVSY DQATSLRILN NGHAFNVEFD DSQDKAVLKG GPLDGTYRLI QFHFHWGSLD GQGSEHTVDK KKYAAELHLV HWNTKYGDFG KAVQQPDGLA VLGIFLKVGS AKPGLQKVVD VLDSIKTKGK SADFTNFDPR GLLPESLDYW TYPGSLTTPP LLECVTWIVL KEPISVSSEQ VLKFRKLNFN GEGEPEELMV DNWRPAQPLK NRQIKASFK
    Specificity
    Ser2-Lys260
    Purity
    > 90 % by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    < 0.1 EU/μg of the protein by LAL method.
    Biological Activity Comment
    Measured by its esterase activity. The specific activity is >840 pmoles/min/μg, as measured with 1 mM 4-Nitrophenyl acetate and 0.1 μg enzyme at 400 nm in 100 μL of 12.5 mM Tris, 75 mM NaCl, pH 7.5.
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    Discover our top product CA2 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH 8.0.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • Target
    CA2 (Carbonic Anhydrase II (CA2))
    Alternative Name
    Carbonic anhydrase 2 (CA2 Products)
    Background

    Description: The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. CA2 is a cytosolic enzyme with the highest activity among all known CAs. Mutations in the CA2 gene result in the CA II deficiency syndrome, an autosomal recessive disorder that produces osteopetrosis, renal tubular acidosis and cerebral calcification.

    Name: CA2, CA-II, CAC, CAII, Car2, HEL-76, HEL-S-282, carbonic anhydrase 2,CA-II,CAC,CAII,Car2,HEL-76,HEL-S-282

    Gene ID
    760
    UniProt
    P00918
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