MERTK Protein (Fc Tag,His tag)

Catalog No. ABIN7519717

Product Details

Target: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This MERTK protein is labelled with Fc Tag,His tag.

Purpose: Active Recombinant Human MERTK Protein

Sequence: REEAKPYPLF PGPFPGSLQT DHTPLLSLPH ASGYQPALMF SPTQPGRPHT GNVAIPQVTS VESKPLPPLA FKHTVGHIIL SEHKGVKFNC SISVPNIYQD TTISWWKDGK ELLGAHHAIT QFYPDDEVTA IIASFSITSV QRSDNGSYIC KMKINNEEIV SDPIYIEVQG LPHFTKQPES MNVTRNTAFN LTCQAVGPPE PVNIFWVQNS SRVNEQPEKS PSVLTVPGLT EMAVFSCEAH NDKGLTVSKG VQINIKAIPS PPTEVSIRNS TAHSILISWV PGFDGYSPFR NCSIQVKEAD PLSNGSVMIF NTSALPHLYQ IKQLQALANY SIGVSCMNEI GWSAVSPWIL ASTTEGAPSV APLNVTVFLN ESSDNVDIRW MKPPTKQQDG ELVGYRISHV WQSAGISKEL LEEVGQNGSR ARISVQVHNA TCTVRIAAVT RGGVGPFSDP VKIFIPAHGW VDYAPSSTPA PGNA

Specificity: Arg26-Ala499

Purity: > 97 % by SDS-PAGE.

Sterility: 0.22 μm filtered

Endotoxin Level: < 1.0 EU/μg of the protein by LAL method.

Biological Activity Comment: 1.Measured by its binding ability in a functional ELISA. Immobilized Human MERTK at 1 μg/mL (100 μL/well) can bind MERTK Rabbit mAb with a linear range of 0.2-3 ng/mL.|2.Measured by its binding ability in a functional ELISA. Immobilized Human Gas6 at 2 μg/mL (100 μL/well) can bind Human MERTK with a linear range of 1-210 ng/mL.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Storage: -20 °C,-80 °C

Storage Comment: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Target Details

Target: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Alternative Name: MERTK (MERTK Products)

Synonyms: MER Protein, RP38 Protein, c-mer Protein, Eyk Protein, Mer Protein, Nyk Protein, nmf12 Protein, rdy Protein, C-EYK Protein, MERTK Protein, DKFZp469D2215 Protein, si:ch1073-268l12.2 Protein, MER proto-oncogene, tyrosine kinase Protein, c-mer proto-oncogene tyrosine kinase Protein, c-mer proto-oncogene tyrosine kinase a Protein, MERTK Protein, Mertk Protein, mertka Protein

Background: MER, RP38, Tyro12, c-Eyk, c-mer,MERTK,RP38,Tyro12,c-Eyk,c-mer

Gene ID: 10461

UniProt: Q12866

Pathways: RTK Signaling