ANGPTL3 Protein (His tag)
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- Target See all ANGPTL3 Proteins
- ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ANGPTL3 protein is labelled with His tag.
- Purpose
- Recombinant Human Angiopoietin-like 3/ANGPTL3 Protein
- Sequence
- SRIDQDNSSF DSLSPEPKSR FAMLDDVKIL ANGLLQLGHG LKDFVHKTKG QINDIFQKLN IFDQSFYDLS LQTSEIKEEE KELRRTTYKL QVKNEEVKNM SLELNSKLES LLEEKILLQQ KVKYLEEQLT NLIQNQPETP EHPEVTSLKT FVEKQDNSIK DLLQTVEDQY KQLNQQHSQI KEIENQLRRT SIQEPTEISL SSKP
- Specificity
- Ser17-Pro220
- Purity
- > 90 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- < 0.1 EU/μg of the protein by LAL method.
- Top Product
- Discover our top product ANGPTL3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- Target
- ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))
- Alternative Name
- Angiopoietin-like 3/ANGPTL3 (ANGPTL3 Products)
- Synonyms
- fb60e11 Protein, fb66h02 Protein, wu:fb60e11 Protein, wu:fb66h02 Protein, zgc:111943 Protein, ANGPTL3 Protein, LOC100230785 Protein, ANG-5 Protein, ANGPT5 Protein, ANL3 Protein, FHBL2 Protein, hypl Protein, angiopoietin-like 3 Protein, angiopoietin like 3 Protein, angptl3 Protein, ANGPTL3 Protein, Angptl3 Protein
- Background
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Description: Angiopoietin-like protein 3 (ANGPTL3) also known as Angiopoietin-related protein 3, Angiopoietin-5 (ANG-5) is a secreted glycoprotein that is structurally related to the angiopoietins.Human ANGPTL3 contains an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain. The fibrinogen C-terminal domain is sufficient to mediate endothelial cell adhesion. ANGPTL3 is principally expressed in the liver and can exert activities related to both angiogenesis and lipid metabolism.ANGPTL3 directly inhibits lipoprotein lipase (LPL) and endothelial lipase (EL), enzymes responsible for hydrolyzing circulating triglycerides and HDL phospholipids.
Name: ANG-5, ANGPT5, ANL3, FHBL2,ANGPTL3,ANGPT5,ANL3,FHBL2
- Gene ID
- 27329
- UniProt
- Q9Y5C1
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