TNFRSF1A Protein (AA 1-212) (His tag)

Catalog No. ABIN7505760

Product Details

Target: TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))

Protein Type: Recombinant

Protein Characteristics: AA 1-212

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This TNFRSF1A protein is labelled with His tag.

Sequence: Met1-Ala212

Characteristics: A DNA sequence encoding the Mouse Tnfrsf1a protein (P25118) (1-212) was expressed with a C-His .

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))

Alternative Name: TNFR1 (TNFRSF1A Products)

Synonyms: CD120a Protein, FPF Protein, MS5 Protein, TBP1 Protein, TNF-R Protein, TNF-R-I Protein, TNF-R55 Protein, TNFAR Protein, TNFR1 Protein, TNFR1-d2 Protein, TNFR55 Protein, TNFR60 Protein, p55 Protein, p55-R Protein, p60 Protein, TNF-R1 Protein, TNF-alphaR1 Protein, TNFRI Protein, TNFRp55 Protein, TNFalpha-R1 Protein, Tnfr-2 Protein, Tnfr1 Protein, fpf Protein, tbp1 Protein, p55-r Protein, tnf-r Protein, tnfar Protein, tnfr1 Protein, cd120a Protein, tnfr55 Protein, tnfr60 Protein, xtnfr1 Protein, wu:fj65b10 Protein, zgc:85914 Protein, TNFR I Protein, TNFRSF1A Protein, TNFA Protein, cTNF Protein, TNF receptor superfamily member 1A Protein, tumor necrosis factor receptor superfamily, member 1a Protein, TNF receptor superfamily member 1A S homeolog Protein, tumor necrosis factor Protein, TNFRSF1A Protein, Tnfrsf1a Protein, tnfrsf1a.S Protein, tnfrsf1a Protein, TNF Protein

Background:

Abbreviation: TNFR1;TNFRSF1A

Target Synonym: CD120a;FPF;p55;p55-R;TNF-alphaR1;TNF-R;TNF-R-I;TNF-R1;TNF-R55;TNFalpha-R1;TNFAR;Tnfr;Tnfr1;TNFR60;TNFRI;TNFRp55

Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD120a (cluste of differentiation 120a), also known as TNFR1 / TNFRSF1A, is a member of CD family, tumor necrosis factor receptor superfamily. CD120a is one of the most primary receptors for the tumor necrosis factor-alpha. It has been shown to be localized to both plasma membrane lipid rafts and the trans golgi complex with the help of the death domain (DD). CD120a can activate the transcription factor NF-κB, mediate apoptosis, and regulate inflammation processes.

Molecular Weight:

Calculated MW: 23.21 kDa

Observed MW: 35 kDa

UniProt: P25118

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Hepatitis C, Ubiquitin Proteasome Pathway