ANGPTL4 Protein (AA 167-410) (His tag)
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- Target See all ANGPTL4 Proteins
- ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 167-410
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ANGPTL4 protein is labelled with His tag.
- Sequence
- Lys167-Ser410
- Characteristics
- A DNA sequence encoding the Mouse ANGPTL4 protein (Q9Z1P8) (Lys167-Ser410) was expressed with a C-His.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product ANGPTL4 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
- Alternative Name
- ANGPTL4 (ANGPTL4 Products)
- Synonyms
- ANGPTL2 Protein, ARP4 Protein, FIAF Protein, HFARP Protein, NL2 Protein, PGAR Protein, pp1158 Protein, Arp4 Protein, Bk89 Protein, Fiaf Protein, Hfarp Protein, Ng27 Protein, Pgar Protein, Pgarg Protein, Pp1158 Protein, ANGPTL4 Protein, fiaf Protein, im:7144703 Protein, si:rp71-39b20.7 Protein, angiopoietin like 4 Protein, angiopoietin-like 4 Protein, ANGPTL4 Protein, Angptl4 Protein, angptl4 Protein
- Background
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Abbreviation: ANGPTL4
Target Synonym: Angiopoietin-related protein 4,425O18-1,Angiopoietin-like protein 4,Fasting-induced adipose factor,Hepatic fibrinogen/angiopoietin-related protein,HFARP,Secreted protein Bk89,Angptl4,Farp,Fiaf,Ng27
Background: Angiopoietin-related protein 4(ANGPTL4)is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.
- Molecular Weight
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Calculated MW: 26.73 kDa
Observed MW: 40 kDa
- UniProt
- Q9Z1P8
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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