SCGB1A1 Protein (AA 1-96) (His tag)
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- Target See all SCGB1A1 Proteins
- SCGB1A1 (Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-96
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SCGB1A1 protein is labelled with His tag.
- Sequence
- Met 1-Phe 96
- Characteristics
- A DNA sequence encoding the Mouse CC17 protein (P11684) (Met 1-Phe 96) was expressed with a C-His.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product SCGB1A1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- SCGB1A1 (Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1))
- Alternative Name
- Uteroglobin (SCGB1A1 Products)
- Synonyms
- CC10 Protein, CC16 Protein, CCPBP Protein, CCSP Protein, UGB Protein, UP-1 Protein, UP1 Protein, UGL Protein, PCB-BP Protein, UG Protein, Utg Protein, PCBB Protein, Ugb Protein, SCGB1A1 Protein, secretoglobin family 1A member 1 Protein, secretoglobin, family 1A, member 1 (uteroglobin) Protein, urinary protein 2 Protein, SCGB1A1 Protein, Scgb1a1 Protein, Rup2 Protein
- Background
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Abbreviation: Uteroglobin,SCGB1A1
Target Synonym: Uteroglobin,Clara cell 17 kDa protein,Clara cell phospholipid-binding protein,CCPBP,Clara cells 10 kDa secretory protein,CC10,PCB-binding protein,Secretoglobin family 1A member 1,Scgb1a1,Cc10,Ugb,CC16,CCSP,PCB-BP,UG,UGB,Utg
Background: Uteroglobin(UG, SCGB1A1) is the founding member of the secretoglobin family of small,secreted, disulfide-bridged dimeric proteins found only in mammals. This protein is mainly expressed in lung, with anti-inflammatory/immunomodulatory properties. CCAAT/enhancer-binding proteins(C/EBPs) are the major transcription factors for the regulation of SCGB1A1 gene expression, whereas FOXA1 had a minimum effect on the transcription. Uteroglobin is a multifunctional protein with anti-inflammatory/immunomodulatory properties. Uteroglobin inhibits soluble phospholipase A(2) activity and binds and perhaps sequesters hydrophobic ligands such as progesterone, retinols, polychlorinated biphenyls, phospholipids, and prostaglandins. In addition to its anti-inflammatory activities, Uteroglobin manifests antichemotactic, antiallergic, antitumorigenic, and embryonic growth-stimulatory activities. Uteroglobin is a potential drug target. The mechanism of Uteroglobin action is likely to be even more complex as it also functions via a putative receptor-mediated pathway.
- Molecular Weight
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Calculated MW: 10.45 kDa
Observed MW: 10 kDa
- UniProt
- Q06318
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