DKK3 Protein (AA 1-349) (His tag)
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- Target See all DKK3 products
- DKK3
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-349
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DKK3 protein is labelled with His tag.
- Sequence
- Met1-Ile349
- Characteristics
- A DNA sequence encoding the Mouse DKK3 protein (Q9QUN9) (Met1-Ile349) was expressed with a C-His.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
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DKK3 (AA 23-350) protein (His-Avi Tag)
Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
DKK3 (AA 23-350) protein (His-Avi Tag,Biotin)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
DKK3 (AA 1-350) protein (GST tag)Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
DKK3 (AA 22-350) protein (His tag)Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- DKK3
- Abstract
- DKK3 Products
- Synonyms
- REIC Protein, RIG Protein, reic Protein, dkk-3 Protein, AW061014 Protein, C87148 Protein, Reic Protein, p29 Protein, dickkopf WNT signaling pathway inhibitor 3 Protein, dickkopf WNT signaling pathway inhibitor 3 S homeolog Protein, DKK3 Protein, dkk3 Protein, dkk3.S Protein, Dkk3 Protein
- Background
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Abbreviation: DKK3
Target Synonym: AW061014,C87148
Background: DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 protein is proposed to function as a secreted tumor suppressor since it is downregulated in a number of cancer cells and prostate cancer tissue and may be a promising candidate molecule for therapeutic interference. DKK3 protein is also a negative regulator of beta-catenin and its downregulation contribute to an activation of the beta-catenin signaling pathway.
- Molecular Weight
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Calculated MW: 38.28 kDa
Observed MW: 60 kDa
- UniProt
- Q9QUN9
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