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CA9 Protein (AA 1-390) (His tag)

CA9 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505747
  • Target See all CA9 Proteins
    CA9 (Carbonic Anhydrase IX (CA9))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-390
    Origin
    • 21
    • 6
    • 3
    • 2
    Mouse
    Source
    • 19
    • 6
    • 4
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CA9 protein is labelled with His tag.
    Sequence
    Met1-Asp390
    Characteristics
    A DNA sequence encoding the Mouse CA9 protein (Q8VHB5) (Met1-Asp390) was expressed with a C-His.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CA9 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    CA9 (Carbonic Anhydrase IX (CA9))
    Alternative Name
    Carbonic Anhydrase 9 (CA9 Products)
    Synonyms
    CA9 Protein, CAIX Protein, Ca9 Protein, MN/CA9 Protein, MN Protein, carbonic anhydrase 9 Protein, CA9 Protein, CAH9 Protein, Car9 Protein
    Background

    Abbreviation: Carbonic Anhydrase 9;CA9

    Target Synonym: RP23-195K8.9;CAIX;Ca9;MN/CA9

    Background: Carbonic anhydrases 9 (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. Cas are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA IX protein is expressed primarily in carcinoma cells lines, and the expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions. It is involved in tumorigenesis through many pathways, such as pH regulation and cell adhesion control. CA IX is used as a marker of tumor hypoxia and as a new therapeutic target for many human carcinomas and cancers.

    Molecular Weight

    Calculated MW: 42.79 kDa

    Observed MW: 50 kDa

    UniProt
    Q8VHB5
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