CD200 Protein (CD200) (AA 1-232) (His tag)
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- Target See all CD200 Proteins
- CD200
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-232
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD200 protein is labelled with His tag.
- Sequence
- Met1-Gly232
- Characteristics
- A DNA sequence encoding the Human CD200 protein (P41217) (Met1-Gly232) was expressed with a C-His.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CD200 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- CD200
- Alternative Name
- CD200 (CD200 Products)
- Synonyms
- MOX1 Protein, MOX2 Protein, MRC Protein, OX-2 Protein, CD200 Protein, Cspmo2 Protein, MRCOX2 Protein, Mox2 Protein, DKFZp459C0716 Protein, OX2 Protein, CD200 molecule Protein, Cd200 molecule Protein, CD200 antigen Protein, CD200 Protein, Cd200 Protein
- Background
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Abbreviation: CD200
Target Synonym: OX-2 Membrane Glycoprotein,CD200,MOX1,MOX2
Background: CD200 is a transmembrane immunoregulatory protein that belongs to the immunoglobulin superfamily. It contains one Ig like V type domain and one Ig like C2 type domain in its extracelluar domain. CD200 is widely but not ubiquitously expressed. Its receptor (CD200R) is restricted primarily to mast cells, basophils, macrophages, and dendritic cells, which suggests myeloid cell regulation as the major function of CD200. CD200 and CD200R associate via their respective N-terminal Ig-like domains. In myeloid cells, CD200R initiates inhibitory signals following receptor-ligand contact. In T cells, CD200 functions as a co-stimulatory molecule independent of the CD28 pathway. In addition, CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.
- Molecular Weight
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Calculated MW: 25.41 kDa
Observed MW: 35 kDa
- UniProt
- P41217
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