Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CD200 Protein (CD200) (AA 1-232) (His tag)

CD200 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505709
  • Target See all CD200 Proteins
    CD200
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-232
    Origin
    • 18
    • 7
    • 2
    • 1
    Human
    Source
    • 13
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CD200 protein is labelled with His tag.
    Sequence
    Met1-Gly232
    Characteristics
    A DNA sequence encoding the Human CD200 protein (P41217) (Met1-Gly232) was expressed with a C-His.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CD200 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    CD200
    Alternative Name
    CD200 (CD200 Products)
    Synonyms
    MOX1 Protein, MOX2 Protein, MRC Protein, OX-2 Protein, CD200 Protein, Cspmo2 Protein, MRCOX2 Protein, Mox2 Protein, DKFZp459C0716 Protein, OX2 Protein, CD200 molecule Protein, Cd200 molecule Protein, CD200 antigen Protein, CD200 Protein, Cd200 Protein
    Background

    Abbreviation: CD200

    Target Synonym: OX-2 Membrane Glycoprotein,CD200,MOX1,MOX2

    Background: CD200 is a transmembrane immunoregulatory protein that belongs to the immunoglobulin superfamily. It contains one Ig like V type domain and one Ig like C2 type domain in its extracelluar domain. CD200 is widely but not ubiquitously expressed. Its receptor (CD200R) is restricted primarily to mast cells, basophils, macrophages, and dendritic cells, which suggests myeloid cell regulation as the major function of CD200. CD200 and CD200R associate via their respective N-terminal Ig-like domains. In myeloid cells, CD200R initiates inhibitory signals following receptor-ligand contact. In T cells, CD200 functions as a co-stimulatory molecule independent of the CD28 pathway. In addition, CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.

    Molecular Weight

    Calculated MW: 25.41 kDa

    Observed MW: 35 kDa

    UniProt
    P41217
You are here: