APOE Protein (AA 1-317) (His tag)
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- Target See all APOE Proteins
- APOE (Apolipoprotein E (APOE))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-317
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This APOE protein is labelled with His tag.
- Sequence
- Met1-His317
- Characteristics
- A DNA sequence encoding the Human ApoE protein (P02649) (Met1-His317) was expressed with a C-His.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product APOE Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- APOE (Apolipoprotein E (APOE))
- Alternative Name
- Apolipoprotein E (APOE Products)
- Synonyms
- ad2 Protein, apoprotein Protein, im:7036787 Protein, wu:fb69a05 Protein, zgc:110064 Protein, apoe Protein, AI255918 Protein, AD2 Protein, LDLCQ5 Protein, LPG Protein, APOEA Protein, Apo-E Protein, apolipoprotein E Protein, apolipoprotein Ea Protein, apoe Protein, apoea Protein, Apoe Protein, APOE Protein
- Background
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Abbreviation: Apolipoprotein E,ApoE
Target Synonym: Apolipoprotein E,APOE,Apo-E
Background: ApoE, a glycoprotein, is a structural component of very low density lipoprotein (vLDL) synthesized by the liver and intestinally synthesized chylomicrons . ApoE is also a constituent of a subclass of high density of lipoproteins (HDL) involved in cholesterol transport .ApoE mediates high affinity binding of chylomicrons and vLDL particles to the LDL receptor, allowing for specific uptake of these particles by the liver, preventing the accumulation of cholesterol rich particles in the plasma .Apolipoprotein E combines with fats (lipids) in the body to form molecules called lipoproteins and Apolipoprotein E is a major component of a specific type of lipoprotein called very low-density lipoproteins (VLDLs).
- Molecular Weight
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Calculated MW: 34.76 kDa
Observed MW: 38 kDa
- UniProt
- P02649
- Pathways
- Regulation of Cell Size, Lipid Metabolism
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