Vitamin D-Binding Protein Protein (GC) (AA 1-474) (His tag)
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- Target See all Vitamin D-Binding Protein (GC) Proteins
- Vitamin D-Binding Protein (GC)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-474
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Vitamin D-Binding Protein protein is labelled with His tag.
- Sequence
- Met1-Leu474
- Characteristics
- A DNA sequence encoding the Human GC protein (P02774) (Met1-Leu4474) was expressed with a C-His .
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product GC Protein
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Vitamin D-Binding Protein (GC) (AA 19-474) protein (His tag)
GC Origin: Human Host: Yeast Recombinant > 90 % SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- Vitamin D-Binding Protein (GC)
- Abstract
- GC Products
- Synonyms
- DBP Protein, DBP/GC Protein, GRD3 Protein, VDBG Protein, VDBP Protein, zgc:110389 Protein, zgc:92753 Protein, GC Protein, Gc Protein, DBP02 Protein, VDB Protein, Vdbp Protein, VTDB Protein, gc Protein, GC, vitamin D binding protein Protein, D-box binding PAR bZIP transcription factor Protein, D site albumin promoter binding protein Protein, group-specific component (vitamin D binding protein) Protein, group specific component Protein, group-specific component (vitamin D binding protein) S homeolog Protein, GC Protein, Dbp Protein, gc Protein, Gc Protein, gc.S Protein
- Background
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Abbreviation: Vitamin D-Binding,GC
Target Synonym: Vitamin D-Binding Protein,DBP,VDB,Gc-Globulin,Group-Specific Component,GC
Background: Vitamin D-Binding Protein (DBP) is a member of the ALB/AFP/VDB family. DBP is a secreted protein and contains three albumin domains. The primary structure contains 28 cysteine residues forming multiple disulfide bonds. DBP acts as a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. DBP binds to vitamin D and its plasma metabolites and transports them to target tissues. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.
- Molecular Weight
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Calculated MW: 52.03 kDa
Observed MW: 57 kDa
- UniProt
- P02774
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, Monocarboxylic Acid Catabolic Process
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