IGHG4 Protein (AA 99-327) (His tag,Fc Tag)
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- Target See all IGHG4 products
- IGHG4 (Immunoglobulin Heavy Constant gamma 4 (G4m Marker) (IGHG4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 99-327
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IGHG4 protein is labelled with His tag,Fc Tag.
- Sequence
- Glu99-Lys327
- Characteristics
- A DNA sequence encoding the Human IgG4 protein (P01861) (Glu99-Lys327) was expressed with a C-His.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
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Immunoglobulin Heavy Constant gamma 4 (G4m Marker) (IGHG4) protein (GST tag)
IGHG4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- IGHG4 (Immunoglobulin Heavy Constant gamma 4 (G4m Marker) (IGHG4))
- Alternative Name
- IGHG4 (IGHG4 Products)
- Synonyms
- immunoglobulin heavy constant gamma 4 (G4m marker) Protein, IGHG4 Protein
- Background
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Abbreviation: IgG4-Fc
Target Synonym: Ig gamma-4 chain C region,IgG4 Fc,IGHG4
Background: SCN3B (sodium channel, voltage-gated, type III, beta ,human IgG1-Fc chimera) belongs to the sodium channel auxiliary subunit SCN3B family. It contains 1 Ig-like C2-type (immunoglobulin-like) domain. Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. SCN3B gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified. Defects in SCN3B are the cause of Brugada syndrome type 7. A tachyarrhythmia characterized by right bundle branch block and ST segment elevation on an electrocardiogram. It can cause the ventricles to beat so fast that the blood is prevented from circulating efficiently in the body. When this situation occurs (called ventricular fibrillation), the individual will faint and may die in a few minutes if the heart is not reset.
- Molecular Weight
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Calculated MW: 25.08 kDa
Observed MW: 35 kDa
- UniProt
- P01861
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