Neurotensin Protein (NTS) (AA 1-148) (His tag)
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- Target See all Neurotensin (NTS) Proteins
- Neurotensin (NTS)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-148
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Neurotensin protein is labelled with His tag.
- Sequence
- Met1-Leu148
- Characteristics
- A DNA sequence encoding the Human NT protein (P30990) (Met1-Leu148) was expressed with a C-His.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product NTS Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- Neurotensin (NTS)
- Alternative Name
- Neurotensin (NTS Products)
- Synonyms
- NTS Protein, NMN-125 Protein, NN Protein, NT Protein, NT/N Protein, NTS1 Protein, 5033428E16Rik Protein, neurotensin Protein, NTS Protein, Nts Protein
- Background
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Abbreviation: Neurotensin,NT
Target Synonym: Neurotensin/neuromedin N,NTS
Background: DPEP2 (MBD-2) belongs to the membrane-bound dipeptidase family. There are three members of this family as membrane-bound dipeptidase-1 (MBD-1),membrane-bound dipeptidase-2 (MBD-2) and membrane-bound dipeptidase-3 (MBD-3).MBD-2 is expressed at highest levels in lung, heart, and testis and at some what lower levels in spleen.MBD-2 is membrane-bound through a glycosylphosphatidyl-inositol linkage and probably is a metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).It is generally recognized that rapid cleavage of LTD4 is important in inactivating the broncho-and vaso-constrictive effects of cysteinyl LTs in asthmatic and inflammatory processes.
- Molecular Weight
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Calculated MW: 16.17 kDa
Observed MW: 35 kDa
- UniProt
- P30990
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