Ephrin A5 Protein (EFNA5) (AA 1-203) (His tag)
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- Target See all Ephrin A5 (EFNA5) Proteins
- Ephrin A5 (EFNA5)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-203
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Ephrin A5 protein is labelled with His tag.
- Sequence
- Met1-Asn203
- Characteristics
- A DNA sequence encoding the Human EFNA5 protein (P52803) (Met1-Asn203) was expressed with a C-His.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product EFNA5 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- Ephrin A5 (EFNA5)
- Alternative Name
- Ephrin-A5 (EFNA5 Products)
- Synonyms
- EFNA5 Protein, af1 Protein, efl5 Protein, rags Protein, eplg7 Protein, lerk7 Protein, AL-1 Protein, AV158822 Protein, EFL-5 Protein, Ephrin-A5 Protein, Epl7 Protein, LERK-7 Protein, RAGS Protein, Lerk7 Protein, AF1 Protein, EFL5 Protein, EPLG7 Protein, GLC1M Protein, LERK7 Protein, ephrin A5 Protein, EFNA5 Protein, efna5 Protein, Efna5 Protein
- Background
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Abbreviation: Ephrin-A5,EFNA5
Target Synonym: Ephrin-A5,EPLG7,LERK7,EFNA5,LERK-7,EPH-related receptor tyrosine kinase ligand 7,AL-1
Background: Ephrin-A5 (EFNA5) belongs to the ephrin family,contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-A5 is a cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. It binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion.
- Molecular Weight
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Calculated MW: 32.67 kDa
Observed MW: 32 kDa
- UniProt
- P52803
- Pathways
- RTK Signaling
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